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Silica Particle Size Standards and Drug Delivery

Silica Nanoparticles, Particle Size Standards and Microbeads

Silica nanoparticles size standards used in Contamination wafer standards and drug delivery.

Silica nanoparticles are particle size standards and spherical in shape. Silicon microbeads are highly accurate, monodisperse, NIST Traceable, size standards and available from 40 nanometers to 2 microns (2000 nm). Silica particles from 40 nm to 102 nm are suspended in ethanol to maintain monodispersity, while Silica particles from 105 nm to 2000 nm are suspended in 15ml DI Water solution. Silica particles have a refractive index quite close to polystyrene latex spheres, making silica particles useful for size calibration with wafer inspection systems, TEMs and SEMs using high powered lasers. Silica particle size standards used in drug delivery and to produce wafer calibration standards and silica contamination wafer standards. Silica microbeads are also available in 5 gram and 10 gram increments, or at any volume desired for industry requirements. Wafer Inspection Systems, SSIS, such as KLA-Tencor SP1, KLA-Tencor SP2, TopCon, ADE and Hitachi Wafer Inspection Systems can use SiO2 particles for size calibration. Silica Nanospheres are provided in particle sizes from 40nm to 2 microns to calibrate the size response curves of the respective wafer inspection systems and laser particle counters. Industries providing Portland cement, CMP slurries, pharmaceutical drug delivery use silica particles from 30nm to 2 microns. Silica microbeads are grown to accurate and repeatable size peaks. Silica nanoparticles are spherical and man made to specific diameters, where as most other process particles are non-spherical and non-uniform in size.

PSL Spheres, SurfCal | PSL Spheres, NIST SRM | PSL Spheres, HEPA Test | OptiBind PSL Spheres | PSL Spheres, HEPA Check

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Description

Product Title (*sizes are similar to NIST SRM sizes)Liquid Volume, (15 ml, 100 ml)Mean PeakSize Uniformity (CV)Silica Particle Concentration by Volume15 ml Volume Bottle100 ml Volume Bottle
Silica Nanoparticles, 40 nm in Ethanol15ml or 100 ml40nm≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 45 nm in Ethanol15ml or 100 ml45nm≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 50 nm in Ethanol15ml or 100 ml50nm≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 60 nm * in Ethanol15ml or 100 ml60nm *≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 70 nm in Ethanol15ml or 100 ml70nm≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 80 nm in Ethanol15ml or 100 ml80nm≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 90 nm in Ethanol15ml or 100 ml90nm≤ 5%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 100 nm in Ethanol15ml or 100 ml100nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 102 nm * in Ethanol15ml or 100 ml102nm *≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 125 nm in Deionized Water15ml or 100 ml125nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 130 nm in Deionized Water15ml or 100 ml130nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 140 nm in Deionized Water15ml or 100 ml140nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 150 nm in Deionized Water15ml or 100 ml150nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 155 nm in Deionized Water15ml or 100 ml155nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 160 nm in Deionized Water15ml or 100 ml160nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 170 nm in Deionized Water15ml or 100 ml170nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 180 nm in Deionized Water15ml or 100 ml180nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 190 nm in Deionized Water15ml or 100 ml190nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 200 nm in Deionized Water15ml or 100 ml200nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 225 nm in Deionized Water15ml or 100 ml225nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 250 nm in Deionized Water15ml or 100 ml250nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 269 nm * in Deionized Water15ml or 100 ml269nm *≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 270 nm in Deionized Water15ml or 100 ml270nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 300 nm in Deionized Water15ml or 100 ml300nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 325 nm in Deionized Water15ml or 100 ml325nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 350 nm in Deionized Water15ml or 100 ml350nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 400 nm in Deionized Water15ml or 100 ml400nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 450 nm in Deionized Water15ml or 100 ml450nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 500 nm in Deionized Water15ml or 100 ml500nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 600 nm in Deionized Water15ml or 100 ml600nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 700 nm in Deionized Water15ml or 100 ml700nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 800 nm in Deionized Water15ml or 100 ml800nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 895 nm * in Deionized Water15ml or 100 ml895nm *≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 1000 nm in Deionized Water15ml or 100 ml1000nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 1019 nm in Deionized Water15ml or 100 ml1019nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 1500 nm in Deionized Water15ml or 100 ml1500nm≤ 3%10%

$495.00Add to cart

$1,495.00Add to cart

Silica Nanoparticles, 2000 nm in Deionized Water15ml or 100 ml2000nm≤ 3%10%

$495.00Add to cart

Silica Nanoparticle as Particle Size Standards and Microbeads:

  • Repeatable, batch to batch, Silica particle diameter size
  • Microbeads are used in pharmaceutical drug delivery
  • Silica nanoparticles are spherical in design and uniform in size
  • Typical <3% Peak Size Distribution Width above 100nm
  • 40nm to 2um Sizes available with 15ml of Di Water and 10% SiO2 concentration
  • 40nm to 30um Sizes available in 1Kg increments of Dry Silica nanoparticles
  • Ultra-High Size Purity of 99.997 percent
  • Refractive Index of SiO2 (n=1.46), very close to Polystyrene Latex (n=1.585) @ 633nm laser wavelength
  • Calibration Curves between SiO2 and PSL Spheres is cose, allowing highly accurate, SiO2 size calibration

Silica Microbeads are Particle Size Standards ordered as a 10% concentration, 15 ml or 100 ml bottles. Call Applied Physics at 720-635-3931.

Silica for Chromatography is accomplished by using silica as the stationary phase in high performance, liquid chromatography (HPLC), ultra high performance liquid chromatography (UHPLC) and hydrophilic interaction chromatography (HILIC) industrial applications. The silica core-type particles are known to achieve higher separation efficiencies than porous particles due to their narrow particle size distributions (PSD). Our high-purity, monodisperse silica with narrow size distribution peak enhances chromatography due to narrow size distribution. The narrow size distribution of silica results in a higher efficiency and consistency due to bed and flow uniformity. The bed uniformity results in a reduced voids and reduced channeling in the silica bed, thus achieving longer life and proposed smaller plate heights. The silica nano-particles are surfaced with silanol groups supporting HILIC in normal phase and HPLC stationary phases. Our Silica is provided as raw material to create a non-polar, functionalized surface, C18, C8, etc., for reversed phase HPLC. Call for sizes needed from the high nanaometers to lower micron sizes.

Industrial Applications Include:

  • Silica Nanospheres and Microbeads
  • Pharmaceutical drug delivery
  • Silica Contamination Wafer Standards
  • Hydrophobic Silica and Functionalized Silica
  • Polymer filler
  • High Pressure, Liquid Chromatography
  • CMP Slurry, Silicon Wafer Polishing
  • Pharmaceutical Drug Delivery and mesoporous silica nanoparticles (MSN)
  • Thin Film, Solar Cell Manufacturing
  • Nano-Composites
  • SSIS (Scanning Surface Inspection Systems) and Aerosol Particle Counter size calibration
  • High Pressure, Liquid Chromatography
  • Portland Cement and Cement manufacturing

Wafer Inspection Systems are Scanning Surface Inspection Systems. SSIS tools, such as Surfscan from KLA, Hitachi and Topcon, can be calibrated using Silica particles, since the refractive index of Silica is close to the refractive index of polystyrene latex. Thus calibration between PSL Spheres and Silica nano-particles are similar. Silica nanoparticles are much more robust to applications using high powered lasers such as the KLA-Tencor SP3, SP5 and SP5xp wafer inspection systems. Silica nano-particles can be ordered by calling Applied Physics at 720-635-3931. The refractive index of Silica nanoparticles is close to the refractive index of Polystyrene latex spheres. Silica particles withstand the high power of laser intensity of high powered lasers, and the Particle Wafer Standards produced using Silica nanoparticles are even longer lasting than with PSL Spheres. Silica particle size standards are available in bulk powder as functionalized silica or hydrophobic silica in 1Kg to 1000 Kg volumes with sizes ranging from 40nm to 2 microns for use in polymer filler. Silica nanoparticles used as size standards are also placed in DI Water solution as 15ml volume and 10% concentration with sizes ranging from 40nm to 2 microns. The use of Silica nanoparticles for SSIS size calibration and Laser Particle Counter, LPC, size calibration is superb, because the Silica particles will not shrink in size when scanned for size calibration by high power lasers used in SSIS and LPC instruments today. SiO2 particle sizes typically requested for SSIS and LPC calibration are 32nm, 40nm, 50nm, 60nm, 70nm, 80nm, 100nm, 125nm, 150nm, 200nm 250nm, 300nm, 400nm, 500nm, 600nm, 750nm, 800nm, 1000nm, 2000nm and 3000nm. Silica particles are also used in pharmaceutical drug delivery.

Silica Particle Size Standards

Silica Particle Size Standards and Drug Delivery From Applied Physics Inc.Silica Particle Size Standards and Drug Delivery From Applied Physics Inc.

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