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Dry-fog decontamination requires a label-directed, validated process. The answers below are not chemical mixing instructions.

Decontamination Using Dry Foggers, QA

  • Can multiple cycles guarantee decontamination of connected rooms and corridors? No. Refilling and restarting alone does not establish efficacy. Define the intended organisms and surfaces, use compatible label-authorized chemistry, and validate distribution, exposure and clearance for the actual rooms and load. CRF4-S, CRF2-S, DF2S and DF4S are equipment names, not guarantees of a successful process.
  • Can you guarantee that fog reaches every area? No. Distribution must be demonstrated under the actual configuration, including obstructions and airflow. A subjective impression or 50–70% relative humidity is not a disinfection endpoint. The current chemical label and validated protocol must specify the required conditions, dose, contact time, monitoring and safe re-entry criteria.
  • Is a six-log reduction determined only by the chemical type or concentration? Neither alone. A six-log reduction means a millionfold reduction under specified test conditions. Results depend on the organism, formulation, application method, exposure, environment and surface or load. EPA registration concerns specific products and labeled uses; it is not blanket approval of any hydrogen peroxide mixture or fogging method.
  • What concentration is required for a six-log reduction? There is no universal concentration. Do not infer a safe or effective recipe from a generic peroxide percentage, a Minncare dilution, or an unsupported kill-rate claim. Follow the current product label and equipment instructions, and establish the required reduction with an appropriate validated test. Increasing concentration can increase hazards without establishing efficacy.
  • Does the CRF4-S cycle include contact time and ventilation? Equipment run time is not the full validated treatment cycle. Contact time, ventilation, residual monitoring and re-entry must follow the current chemical label and site-specific procedure. A fixed 15-minute dwell or three air changes cannot be assumed to establish efficacy or safe occupancy.
  • Can cycle times and duration be stored? Confirm logging and remote-control functions for the exact current model and configuration with Applied Physics. Historical references to CRF2-S, CRF4-S, DF2S and DF4S do not establish current data-storage capability or validated room capacity.
  • Are rental or demonstration units available? Contact Applied Physics for current availability and terms. Historical demand statements do not establish today’s rental policy.
  • How do CRF2-S, CRF4-S, DF2S and DF4S compare? Compare current manufacturer documentation for output, controls, utilities, compatible liquids and service requirements. A nominal enclosure volume is not a demonstrated disinfection or sterilization capacity. Select equipment against the actual application and validated process rather than universal room-volume or wireless-control claims.
appliedphysicsusa | econtamination Using Dry Foggers, Q&A
Decontamination Using Dry Foggers, Q&A

Reference: EPA guidance on fogging, fumigation and electrostatic application. EPA has not evaluated safety and efficacy for fogging when that method is absent from the product label.

APPLIED PHYSICS TECHNICAL RESOURCE

Continue from the technical question to the application

Airflow visualization, smoke studies, tracer delivery, particle monitoring and controlled-environment validation. Product and standards references should be interpreted for the actual instrument, facility, protocol and configuration.

Cleanroom validation
Cleanroom foggers
ISO 14644-3 smoke studies
Technical publications
Discuss the application
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