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Applied Physics Corporation

AP200 Ultrapure Cleanroom Fogger – Maximum Fog Volume for Large-Scale Cleanroom Validation

AP200 Ultrapure Cleanroom Fogger – Maximum Fog Volume for Large-Scale Cleanroom Validation

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Description

The AP200 Ultrapure Cleanroom Fogger is the most powerful liquid nitrogen (LN₂) fogging system in its class, designed for large-scale cleanroom validation, airflow visualization, and contamination control. Engineered for high-volume fog generation, the AP200 delivers industry-leading fog output, extended runtime, and unmatched efficiency, making it the premier choice for semiconductor fabs, pharmaceutical cleanrooms, and aerospace facilities.

Using LN₂ and deionized water, the AP200 produces ultra-dense, residue-free fog to precisely visualize airflow, pressure dynamics, and filtration efficiency in ISO 3–7 environments. With 28.6 cubic meters of fog per minute, the AP200 far surpasses standard cleanroom foggers, enabling faster and more comprehensive cleanroom validation.


Why Choose the AP200?

Industry-Leading Fog Volume – Generates up to 28.6 cubic meters of ultra-dense fog per minute, allowing for rapid large-area cleanroom testing.
Longest Runtime – Optimized LN₂ and DI water consumption provides up to 105 minutes of continuous operation, outperforming standard cleanroom foggers.
Ultra-Pure, Zero-Residue Fog – Produces 100% clean, particle-free fog, ensuring compliance with ISO 14644, GMP, and FDA validation standards.
Ideal for Large Cleanrooms & Manufacturing EnvironmentsSupports extensive airflow visualization in semiconductors, pharmaceuticals, aerospace, and biomedical research facilities.
Maximum Efficiency & Cost SavingsReduces LN₂ consumption per cubic meter of fog, lowering operational costs compared to alternative fogging solutions.
Reliable HEPA & Laminar Flow TestingEnsures precision airflow tracing without introducing fog residue or contaminating cleanroom environments.


Performance Comparison: AP200 vs. Other Cleanroom Foggers

Feature AP200 Ultrapure Fogger Other LN₂ Foggers Alternative Foggers
Fog Volume 28.6 m³/min 15–20 m³/min 3.5–10 m³/min
Fog Purity 100% Ultrapure LN₂ Fog Ultrapure LN₂ Fog Chemical-Based Fog
Run Time 105 min 60–75 min 30–50 min
Residue-Free Yes Yes No
Portable Design Yes Often Bulkier Varies
ISO/GMP Compliance Yes Yes Some

The AP200 delivers superior fog output and extended runtime, making it the go-to solution for high-volume cleanroom validation.


Applications for the AP200 Ultrapure Cleanroom Fogger

🔹 ISO 14644 airflow visualization – Detect turbulence, pressure variations, and airflow inefficiencies in large cleanrooms.
🔹 HEPA filter validation & leak detection – Verify laminar flow performance in pharmaceutical and semiconductor facilities.
🔹 Semiconductor & aerospace cleanroom testingEnsure clean airflow dynamics in critical manufacturing environments.
🔹 GMP-compliant pharmaceutical validation – Support FDA and EU GMP regulations with pure, contamination-free fog.
🔹 Large-scale airflow mapping & contamination control – Ideal for biotech labs, nuclear facilities, and high-security clean zones.

Unlike alternative foggers that struggle with high-volume cleanroom testing, the AP200 offers the highest fog production available, without compromising purity or efficiency.


Upgrade to the AP200 – The Ultimate High-Volume Cleanroom Fogger

For large-scale cleanroom validation, airflow visualization, and HEPA testing, the AP200 Ultrapure Cleanroom Fogger provides unmatched fog density, runtime, and efficiency.

📞 Contact us today for a quote and upgrade to the most advanced ultrapure fogging system available.


Watch video of the LN2 UltraPure Fogger

Compare AP35, AP100 Ultrapure LN2 Fogger, CRF6 Cleanroom Fogger and CRF3 Cleanroom  Fogger

 

Product Model AP100 LN2 Fogger AP35 LN2 Fogger CRF6 Cleanroom Fogger CRF3 Cleanroom Fogger
FOG Minutes about 90 minutes 60 - 70 minutes about 35 minutes from 70 minutes
FOG Volume (Cu. M. per Min) about 15.5 cu. Meters per min, 2 to 4 fog hoses about 5.0 cu. Meters per min, 1 to 2 fog hoses about 2.0 cubic meters per minute thru dual 80mm fog outlets about 0.89 cubic meters per minute thru one 80mm fog outlet
FOG Volume (Cu. Meters) about 1162 cu. M. about 350 cu. M. about 70 cu. M. about 60 cu. M.
Fog Density (milli-liters per min.) about 1520 mL per min. about 571 mL per min. about 213.7 mL per min. about 89 ml per min.
Visual Fog Distance in feet about 30 - 40 ft about 20 - 30 ft about 12 - 15 ft about 10 ft
Fog Volume Adjustments Yes, through hand valve control Yes, through hand valve control Yes, through touchpad and wireless control Yes, through touchpad and wireless control
Airflow Velocity Adjustments through touchpad and wireless through touchpad and wireless through touchpad and wireless Yes, through touchpad and wireless control
Equipment Design Ultrapure Ultrapure Ultrasonic Ultrasonic
Liquids Used LN2 + DI Water, Sterile Water or WFI LN2 + DI Water, Sterile Water or WFI DI Water, Sterile Water or WFI Water DI Water, Sterile Water or WFI Water
Class of Cleanroom Class 1 to 10000 or stage Fog Class 1 to 10000 Class 1 to 10000 Class 1 to 10000
Smoke Study Guides USP 797 USP 797 USP 797 USP 797
Other Guidelines ISO 14644-3, Annex B7 ISO 14644-3, Annex B7 ISO 14644-3, Annex B7 ISO 14644-3, Annex B7
Federal Standards Federal Standards 209E Federal Standards 209E Federal Standards 209E Federal Standards 209E
ISO Compliance ISO Standard 14644-1, 14644-2 ISO Standard 14644-1, 14644-2 ISO Standard 14644-1, 14644-2 ISO Standard 14644-1, 14644-2
Deionized, Sterile or WFI Volume 10 L, 2 internal water heaters 5 L, 2 internal water heaters 9.0 L 9.5 L
LN2 Volume 100 liters 35 liters No LN2 used No LN2 used
Operator Control Touchpad control of airflow Touchpad control of airflow Touchpad control of fog volume & airflow velocity
Touchpad control of fog volume & airflow velocity
Wireless Control Airflow Wireless control Airflow Wireless control Wireless control or airflow and fog volume Wireless control or airflow and fog volume
Handles or Wheels Wheels on SS Enclosure Wheels on SS Enclosure Carry Handles on top and front Carry Handles on top and front
Construction electro polish 316L Stainless Steel electro polish 316L Stainless Steel electro polish 316L Stainless Steel electro polish 316L Stainless Steel
Plug in Power 220 VAC 120, 220, 100 VAC 120, 220, 100 VAC 120, 220, 100 VAC
Weight with Full Liquids about 398 pounds about 250 pounds about 65 pounds about 40 pounds
Accessories 1-12 optional Accs 1-12 optional Accs 1-12 optional Accs 1-12 optional Accs

 

INFORMATION

The AP200 Ultrapure Fogger is used in smoke studies requiring higher volumes of ultrapure fog. No fog contamination and no clean room clean up is required after use. Operating instructions are emailed as a PDF manual.

Theory of Operation: Ultrapure fog generation using liquid nitrogen and DI water or WFI Water. Use of any other liquids or chemicals will void the warranty.

Direct operation or wireless remote control operation is provided.
Notes:

  1. The AP200 produces higher volumes of ultrapure fog with a fog vapor diameter of 2-3 microns. AVOID USING IN IMMEDIATE VICINITY OF ELECTRICAL APPLIANCES, WATER SENSITIVE PRODUCTS AND EQUIPMENT.
  2. The LN2 fogger is intended for use on a flat surface. DO NOT OVERFILL OR TIP THE FOGGER DURING OPERATION.

 

Cleanroom Ultrapure Fogger Features

 

Ultrapure Nitrogen Fog Generator with Fog Curtain
  • Adjustable volume of ultrapure fog to visualize airflow and describe direction, velocity and patterns in airflow
  • Modular design provides a simple design and easy operation
  • Standard Direct Control, or remote control by wireless key fob to operate behind a closed wall or closed area
  • Visualize unwanted gas emission locations and dead zones
  • Testing with ISO 14644-3 ANNEX B7 airflow visualization
  • Testing with Federal Standards 209E in semiconductor cleanrooms
  • Testing with Pharmaceutical USP 797 Guidelines and airflow visualization
  • Testing with NSF 49 National Safety Foundation for airflow visualization
  • Testing with the USP 800 Hazardous Drug Compounding for airflow visualization
  • Supports airflow visualization test for Semiconductor Semi-Standards Guidelines
  • Track routes of unwanted air flow infiltration and air balance of clean rooms
  • No particle contamination created, no particle contamination left behind, evaporating back to air we breathe
  • No cleanup of any kind after fogging of airflow
  • Superb 3D airflow modeling capabilities with high density fog, 533ml per minute converted to fog
  • Very low fog exit pressure, no exit turbulence as fog enters airflow
  • Compact, transportable, shipping case
  • Standard fog stream output from 5 meter transparent fog hose
  • For use in sterile rooms, medical rooms, ISO 1 to 9 suites and semiconductor clean rooms
  • High density fog visualization provides the best airflow visualization of any fogger in the market
  • Exhaust and ventilation studies around wafer handling systems
  • Air balance studies in Pharmaceutical suites and clean rooms

 

Cleanroom Ultrapure Fogger Advantages - Request a Quote

  • Highest fog density by converting 571 ml of liquid per minute to an ultrapure fog
  • Greatest visible airflow distances of 20 to 30 feet
  • Excellent volume of ultrapure fog at 5 cubic meters per minute
  • Total volume of 375 cubic meters of ultrapure fog per operating cycle
  • Fog operating time of about 70 minutes
  • No contamination is created, no cleanup is required, no contamination to the process
  • Adjustable fog volume and velocity to tune fog to your clean room dynamics
  • Roller castors for easy movement over floor
  • 80mm wide fog hose, 3.15"
  • User Friendly display and touch pads or wireless remote control FOB
  • Stainless steel contacts the LNG and DI Water for best purity of fog
  • very low fog exit pressure that does not create a disturbance to airflow
  • No metal contamination to fog using Stainless Steel water heater and LNG Dewar
  • Optional High Contrast Light accessory to provide high contrast between visualized airflow and background
  • Optional 350 mm Fog Nozzle accessory to spread standard fog stream out around equipement
  • Optional Y Adaptor accessory to convert single fog output into two separate fogger hoses for two separate fog inputs to your clean room
  • Optional T Adaptor accessory to convert single fog output into two Fog Curtain Wands to spread fog pattern out across wide area
  • Optional Y Adaptor for 2 fog hose output from AP35
  • Optional 1.3 Meter Fog Curtain Wand to spread fog stream out into a wide fog pattern
  • Easy DI Water and LN2 (LNG) fill up

* Fog distance measured at 40% humidity and air velocity of 90fpm. Visual fog distance decreases as humidity decreases or as airflow velocity increases.

 

Which Smoke Generator Is Better For Smoke Studies?

Cleanroom UltraPure Fogger, 5 Cubic Meters per minute for 70 minutes with 20-30 feet visible distance.
  • When high fog purity, high fog volume and long visible airflow is needed
  • To visualizing airflow in large clean rooms, ceiling to floor
  • To fog exit velocity must not create turbulence
  • To needing to do 3D airflow modeling of airflow
  • When needing to do visualize airflow in larger cleanrooms
  • When 70 minutes of high purity fog duration is needed
  • When fog visibility of 20-30 feet distance is required
  • To fog Class 1 to Class 10,000 semiconductor, medical, pharmaceutical clean rooms

* Use Hand Gloves and Face Shield when filling LN2
Use 16M ohm DI water or WFI Pharmaceutical Water

Clean Room Fogger, 9cfm, 50 minutes Operation
  • When budget is lower, basic Fogger OK, minimal output turbulence
  • When 50 minutes of fog duration is useful with quick turnaround
  • When fog visibility for 7-8 feet distance is acceptable
  • When fogging gray areas behind the cleanroom
  • When fogging ≥ Class 10 or above in semiconductor or pharmaceutical clean rooms
CO2 Fogger, Vapor DiH2O Fogger, average 4cfm over 10 minutes
  • When Fogging Hazardous areas, No Electrical Outlet Available
  • When fog visibility for 4-6 feet distance is acceptable
  • When 10 minutes of fog duration is useful
  • When fogging small areas
  • Class 10 or above in semiconductor or pharmaceutical clean rooms
  • When fogging work benches

16 Meg ohm DI water is standard or WFI Water
Do not permit DI Water to go stagnant in the water chamber
** Use gloves when handling CO2 ice