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Applied Physics Corporation

AP50 Ultrapure Cleanroom Fogger – High-Performance LN₂ Fogging for Airflow Visualization & Validation

AP50 Ultrapure Cleanroom Fogger – High-Performance LN₂ Fogging for Airflow Visualization & Validation

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Description

The AP50 Ultrapure Cleanroom Fogger is a powerful liquid nitrogen (LN₂) fogging system, engineered for cleanroom validation, airflow visualization, and contamination control. As part of the next generation of ultrapure fogging solutions, the AP50 provides greater fog volume, extended runtime, and increased efficiency over previous models, making it an ideal replacement for traditional cleanroom foggers.

By utilizing LN₂ and deionized water, the AP50 generates ultra-dense, residue-free fog, ensuring clear, contaminant-free airflow tracking in ISO 3–7 cleanrooms. Whether conducting GMP audits, HEPA filter testing, or airflow turbulence analysis, the AP50 delivers exceptional visibility and performance.


Why Upgrade to the AP50?

Higher Fog Volume & Coverage – Produces up to 7.1 cubic meters of ultrapure fog per minute, providing greater airflow tracing and turbulence mapping over previous models.
Extended Runtime – With optimized LN₂ and DI water consumption, the AP50 runs for up to 75 minutes, outlasting many standard cleanroom foggers.
Zero-Residue Fog – Generates 100% pure, non-contaminating fog, meeting ISO 14644, GMP, and FDA validation requirements.
Optimized Efficiency – Produces more fog per liter of LN₂, reducing operational costs and increasing effectiveness in cleanroom airflow testing.
Portable & Compact DesignLightweight and transportable, the AP50 allows for easy maneuverability in cleanrooms, unlike bulkier fogging units.
HEPA & Laminar Flow Testing – Designed to accurately reveal airflow pathways without introducing false positives or contamination in filter validation.


Performance Comparison: AP50 vs. Other Cleanroom Foggers

Feature AP50 Ultrapure Fogger Other LN₂ Foggers Alternative Foggers
Fog Volume 7.1 m³/min 5.0–6.5 m³/min 2.5–5.0 m³/min
Fog Purity 100% Ultrapure LN₂ Fog Ultrapure LN₂ Fog Chemical-Based Fog
Run Time 75 min 45–60 min 30–45 min
Residue-Free Yes Yes No
Portable Design Yes Often Bulkier Varies
ISO/GMP Compliance Yes Yes Some

With increased fog output and extended runtime, the AP50 sets a new standard for precision airflow visualization in pharmaceutical, semiconductor, and aerospace environments.


Applications for the AP50 Ultrapure Cleanroom Fogger

🔹 ISO 14644 airflow visualization – Detect air turbulence, leaks, and pressure differentials in contamination-controlled environments.
🔹 HEPA filter testing & validation – Verify laminar flow efficiency and filter containment without false positives.
🔹 Semiconductor & biotech cleanroom testingVisualize airflow paths in critical ISO 3–7 cleanrooms.
🔹 GMP-compliant pharmaceutical validation – Ensure cleanroom air quality meets FDA and EU GMP regulations.
🔹 Aerospace & clean manufacturing airflow mapping – Test particle containment and airflow balance in mission-critical facilities.

Unlike foggers using chemical-based fogging agents, the AP50 ensures particle-free, non-contaminating fog production, making it one of the most effective cleanroom foggers available today.


Experience the Next Level of Cleanroom Fogging with the AP50

The AP50 Ultrapure Cleanroom Fogger is designed to meet the highest standards in airflow visualization, contamination control, and cleanroom validation.

📞 Contact us today for a quote and upgrade to the most advanced ultrapure fogging system available.


 

Watch video of the LN2 UltraPure Fogger

Compare AP35, AP100 Ultrapure LN2 Fogger, CRF6 Cleanroom Fogger and CRF3 Cleanroom  Fogger

 

Product Model AP100 LN2 Fogger AP35 LN2 Fogger CRF6 Cleanroom Fogger CRF3 Cleanroom Fogger
FOG Minutes about 90 minutes 60 - 70 minutes about 35 minutes from 70 minutes
FOG Volume (Cu. M. per Min) about 15.5 cu. Meters per min, 2 to 4 fog hoses about 5.0 cu. Meters per min, 1 to 2 fog hoses about 2.0 cubic meters per minute thru dual 80mm fog outlets about 0.89 cubic meters per minute thru one 80mm fog outlet
FOG Volume (Cu. Meters) about 1162 cu. M. about 350 cu. M. about 70 cu. M. about 60 cu. M.
Fog Density (milli-liters per min.) about 1520 mL per min. about 571 mL per min. about 213.7 mL per min. about 89 ml per min.
Visual Fog Distance in feet about 30 - 40 ft about 20 - 30 ft about 12 - 15 ft about 10 ft
Fog Volume Adjustments Yes, through hand valve control Yes, through hand valve control Yes, through touchpad and wireless control Yes, through touchpad and wireless control
Airflow Velocity Adjustments through touchpad and wireless through touchpad and wireless through touchpad and wireless Yes, through touchpad and wireless control
Equipment Design Ultrapure Ultrapure Ultrasonic Ultrasonic
Liquids Used LN2 + DI Water, Sterile Water or WFI LN2 + DI Water, Sterile Water or WFI DI Water, Sterile Water or WFI Water DI Water, Sterile Water or WFI Water
Class of Cleanroom Class 1 to 10000 or stage Fog Class 1 to 10000 Class 1 to 10000 Class 1 to 10000
Smoke Study Guides USP 797 USP 797 USP 797 USP 797
Other Guidelines ISO 14644-3, Annex B7 ISO 14644-3, Annex B7 ISO 14644-3, Annex B7 ISO 14644-3, Annex B7
Federal Standards Federal Standards 209E Federal Standards 209E Federal Standards 209E Federal Standards 209E
ISO Compliance ISO Standard 14644-1, 14644-2 ISO Standard 14644-1, 14644-2 ISO Standard 14644-1, 14644-2 ISO Standard 14644-1, 14644-2
Deionized, Sterile or WFI Volume 10 L, 2 internal water heaters 5 L, 2 internal water heaters 9.0 L 9.5 L
LN2 Volume 100 liters 35 liters No LN2 used No LN2 used
Operator Control Touchpad control of airflow Touchpad control of airflow Touchpad control of fog volume & airflow velocity
Touchpad control of fog volume & airflow velocity
Wireless Control Airflow Wireless control Airflow Wireless control Wireless control or airflow and fog volume Wireless control or airflow and fog volume
Handles or Wheels Wheels on SS Enclosure Wheels on SS Enclosure Carry Handles on top and front Carry Handles on top and front
Construction electro polish 316L Stainless Steel electro polish 316L Stainless Steel electro polish 316L Stainless Steel electro polish 316L Stainless Steel
Plug in Power 220 VAC 120, 220, 100 VAC 120, 220, 100 VAC 120, 220, 100 VAC
Weight with Full Liquids about 398 pounds about 250 pounds about 65 pounds about 40 pounds
Accessories 1-12 optional Accs 1-12 optional Accs 1-12 optional Accs 1-12 optional Accs

 

INFORMATION

The AP35 Ultrapure Fogger is used in smoke studies requiring higher volumes of ultrapure fog. No fog contamination and no clean room clean up is required after use. Operating instructions are emailed as a PDF manual.

Theory of Operation: Ultrapure fog generation using liquid nitrogen and DI water or WFI Water. Use of any other liquids or chemicals will void the warranty.

Direct operation or wireless remote control operation is provided.
Notes:

  1. The AP35 produces higher volumes of ultrapure fog with a fog vapor diameter of 2-3 microns. AVOID USING IN IMMEDIATE VICINITY OF ELECTRICAL APPLIANCES, WATER SENSITIVE PRODUCTS AND EQUIPMENT.
  2. The LN2 fogger is intended for use on a flat surface. DO NOT OVERFILL OR TIP THE FOGGER DURING OPERATION.

 

Cleanroom Ultrapure Fogger Features

 

Ultrapure Nitrogen Fog Generator with Fog Curtain
  • Adjustable volume of ultrapure fog to visualize airflow and describe direction, velocity and patterns in airflow
  • Modular design provides a simple design and easy operation
  • Standard Direct Control, or remote control by wireless key fob to operate behind a closed wall or closed area
  • Visualize unwanted gas emission locations and dead zones
  • Testing with ISO 14644-3 ANNEX B7 airflow visualization
  • Testing with Federal Standards 209E in semiconductor cleanrooms
  • Testing with Pharmaceutical USP 797 Guidelines and airflow visualization
  • Testing with NSF 49 National Safety Foundation for airflow visualization
  • Testing with the USP 800 Hazardous Drug Compounding for airflow visualization
  • Supports airflow visualization test for Semiconductor Semi-Standards Guidelines
  • Track routes of unwanted air flow infiltration and air balance of clean rooms
  • No particle contamination created, no particle contamination left behind, evaporating back to air we breathe
  • No cleanup of any kind after fogging of airflow
  • Superb 3D airflow modeling capabilities with high density fog, 533ml per minute converted to fog
  • Very low fog exit pressure, no exit turbulence as fog enters airflow
  • Compact, transportable, shipping case
  • Standard fog stream output from 5 meter transparent fog hose
  • For use in sterile rooms, medical rooms, ISO 1 to 9 suites and semiconductor clean rooms
  • High density fog visualization provides the best airflow visualization of any fogger in the market
  • Exhaust and ventilation studies around wafer handling systems
  • Air balance studies in Pharmaceutical suites and clean rooms

 

Cleanroom Ultrapure Fogger Advantages - Request a Quote

  • Highest fog density by converting 571 ml of liquid per minute to an ultrapure fog
  • Greatest visible airflow distances of 20 to 30 feet
  • Excellent volume of ultrapure fog at 5 cubic meters per minute
  • Total volume of 375 cubic meters of ultrapure fog per operating cycle
  • Fog operating time of about 70 minutes
  • No contamination is created, no cleanup is required, no contamination to the process
  • Adjustable fog volume and velocity to tune fog to your clean room dynamics
  • Roller castors for easy movement over floor
  • 80mm wide fog hose, 3.15"
  • User Friendly display and touch pads or wireless remote control FOB
  • Stainless steel contacts the LNG and DI Water for best purity of fog
  • very low fog exit pressure that does not create a disturbance to airflow
  • No metal contamination to fog using Stainless Steel water heater and LNG Dewar
  • Optional High Contrast Light accessory to provide high contrast between visualized airflow and background
  • Optional 350 mm Fog Nozzle accessory to spread standard fog stream out around equipement
  • Optional Y Adaptor accessory to convert single fog output into two separate fogger hoses for two separate fog inputs to your clean room
  • Optional T Adaptor accessory to convert single fog output into two Fog Curtain Wands to spread fog pattern out across wide area
  • Optional Y Adaptor for 2 fog hose output from AP35
  • Optional 1.3 Meter Fog Curtain Wand to spread fog stream out into a wide fog pattern
  • Easy DI Water and LN2 (LNG) fill up

* Fog distance measured at 40% humidity and air velocity of 90fpm. Visual fog distance decreases as humidity decreases or as airflow velocity increases.

 

Which Smoke Generator Is Better For Smoke Studies?

Cleanroom UltraPure Fogger, 5 Cubic Meters per minute for 70 minutes with 20-30 feet visible distance.
  • When high fog purity, high fog volume and long visible airflow is needed
  • To visualizing airflow in large clean rooms, ceiling to floor
  • To fog exit velocity must not create turbulence
  • To needing to do 3D airflow modeling of airflow
  • When needing to do visualize airflow in larger cleanrooms
  • When 70 minutes of high purity fog duration is needed
  • When fog visibility of 20-30 feet distance is required
  • To fog Class 1 to Class 10,000 semiconductor, medical, pharmaceutical clean rooms

* Use Hand Gloves and Face Shield when filling LN2
Use 16M ohm DI water or WFI Pharmaceutical Water

Clean Room Fogger, 9cfm, 50 minutes Operation
  • When budget is lower, basic Fogger OK, minimal output turbulence
  • When 50 minutes of fog duration is useful with quick turnaround
  • When fog visibility for 7-8 feet distance is acceptable
  • When fogging gray areas behind the cleanroom
  • When fogging ≥ Class 10 or above in semiconductor or pharmaceutical clean rooms
CO2 Fogger, Vapor DiH2O Fogger, average 4cfm over 10 minutes
  • When Fogging Hazardous areas, No Electrical Outlet Available
  • When fog visibility for 4-6 feet distance is acceptable
  • When 10 minutes of fog duration is useful
  • When fogging small areas
  • Class 10 or above in semiconductor or pharmaceutical clean rooms
  • When fogging work benches

16 Meg ohm DI water is standard or WFI Water
Do not permit DI Water to go stagnant in the water chamber
** Use gloves when handling CO2 ice