Applied Physics · Precision technologies since 1992
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Particle Size Standards

Browse PSL, silica, glass and specialized particles for calibration, metrology and laboratory applications. Select the material, nominal size and physical form required by your method.

Particle Size Standards · Selection Guide

Select the particle standard by material, size, form and measurement objective

The fastest path to the right quote is to specify what the instrument is measuring and the physical form the workflow actually requires.

Material

Choose PSL, silica or another material required by the method.

Nominal size

Provide target diameter or size set and the tolerance/certificate requirement.

Delivery form

Specify suspension, dry powder, deposited wafer or another prepared reference.

Instrument / application

RFQ data

RFQ Conversion Checklist

Send a quote-ready particle-standard request

What AP should return

Use the product quote control. Your selected product, variation and quantity will remain attached to the request while you add application and technical details.

Technical FAQ

Questions engineers and validation teams ask

Provide the instrument or application, particle material, nominal size or size set, delivery form, certificate or traceability requirement, quantity and target delivery date.
No. Select the particle material required by the instrument, SOP or study objective rather than substituting only by nominal diameter.
For a deposited wafer, specify wafer diameter/substrate, particle material and size, deposition geometry and inspection-tool/recipe objective.

Material → Measurement Objective

Choose particle material from the method—not from the product name

Material / familyStart here when the requirement is…Quote variables
PSL / polystyrene latexMonodisperse particle-size references, particle-counter/optical calibration, aerosol work, or deposited wafer references.Instrument/application, nominal size(s), form/concentration, quantity, certificate/traceability.
Silica / SiO₂Silica reference behavior, contamination-wafer work, optical/material research, or functionalized silica formulations.Size, surface treatment/functionalization, powder vs suspension, solvent/concentration, quantity.
Borosilicate / glassPowder/particle-size measurement and methods where glass material properties and available size ranges are appropriate.Method/instrument, nominal size/range, quantity, sample preparation and documentation.
Fluorescent / dyed polymerImaging, tracking, optical method development, method visibility or research requiring a colored/fluorescent signal.Size, color/excitation-emission, surface chemistry, dry/suspension form, concentration/quantity.
Functionalized / assay particlesConjugation, binding, lateral-flow, diagnostic or assay-development workflows.Core material, size, functional group/coating, concentration, conjugation target and assay conditions.
Magnetic / metallic nanoparticlesResearch workflows where magnetic response, plasmonic/optical properties or specialized surface chemistry are part of the method.Composition, size, morphology, coating/functionalization, concentration and application.

Particle Standards & Microspheres

Route the buyer from application to the right particle family

Particle-counter calibration

Start with PSL or another method-specified reference size. Capture the instrument/model, channel or target diameter, procedure and documentation requirement.

Semiconductor / SSIS

Use particle suspensions or deposited wafers according to the inspection tool, substrate, recipe and calibration objective.

HEPA / aerosol challenge

Separate the particle reference from the aerosol-generation/dilution method. Specify the test method, target size and equipment context.

Fluorescent imaging / tracking

Choose size plus fluorescent properties, surface chemistry and form around the imaging or tracking method.

Assays / diagnostics

Choose functional group, particle size, material and concentration around conjugation chemistry and assay architecture.

Materials & nanoparticle research

Choose core composition, size, coating/functionalization, concentration/form and method-specific documentation.

Make the particle inquiry quote-ready

Do not let the catalog make the engineering decision

Applied Physics has overlapping particle families and many individual size SKUs. The correct quote should be driven by the customer’s method and required reference properties—not by whichever product title happens to rank first.

For an accurate quote: use the product quote control so the selected product, variation and quantity remain attached to your request.

REFERENCE SELECTION

Choose the standard by material, physical form and measurement method

The same nominal diameter can serve very different purposes. Start with the instrument and the physical reference it can actually use.

PSL / polystyrene

Low-density, optically useful reference spheres available across nanometer and micron-scale families.

Silica & glass

Higher-density materials with different optical, surface and handling behavior.

Fluorescent / dyed

Particles selected by optical response as well as diameter for imaging, flow and tracer work.

Functionalized

Surface-modified particles for coupling, assay, diagnostic and research-development workflows.

Aqueous suspension

Ready for compatible liquid, microscopy, aerosol-generation or deposition workflows.

Dry powder

Requires a defined dispersion, handling and agglomeration-control method.

Deposited wafer

Adds substrate, surface and deposition geometry for SSIS or wafer-inspection work.

Count control

Adds a defined concentration for liquid particle-counter counting or volumetric checks.

Common applications

Method-specific guardrail

ISO 21501-4 addresses calibration and verification of light-scattering airborne particle counters, including size setting, counting efficiency and related performance characteristics. It does not make every microsphere a universal standard.

Confirm the exact instrument, medium, nominal channel, concentration, certificate and acceptance procedure before ordering.

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